Endocrine Abstracts

Arginine vasopressin (AVP) is secreted via exocytosis; however, the precise molecular mechanism underlying the exocytosis of AVP is unknown. To better understand the mechanisms of AVP secretion, here we study to identify proteins that bind with a 25 kDa synaptosomal-associated protein (SNAP25), a protein that plays a crucial role in exocytosis, in the posterior pituitary. Embryonic stem (ES) cell-derived AVP neurons were established to investigate the functions of the identifi...